Solace operates internationally with bases in Boston, USA and Canterbury, UK. Solace has a small, experienced team of pharmaceutical research and development staff that work through a 'virtual' business model to deliver the company's projects. The business has adopted the 'Mission Command' principles of management, in which every member of the organization are empowered to use their initiative and judgment to exploit opportunities in the context of the mission of the company.

To achieve its mission, Solace had created a sophisticated and extensive network of partners and suppliers specializing in discovering and developing treatments for pain.